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. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183

Table 3.

Absolute values for remodeling markers in the airway.

Remodeling markers SAL OVA OVA-RHOi OVA-anti-IL17 OVA-RHOi-anti-IL17
Airway MMP-9 (cells/104μm2) 2.4 ± 0.75 7.25 ± 1.79 3.49 ± 0.82∗∗ 2.36 ± 0.72∗∗ 1.37 ± 0.46∗∗
Airway MMP-12 (cells/104μm2) 0.51 ± 0.35 9.78 ± 0.81 0.51 ± 0.3∗∗ 2.08 ± 0.84∗∗ 2.35 ± 0.88∗∗
Airway TIMP-l (cells/104μm2) 0.21 ± 0.21 6.11 ± 1.24 1.57 ± 0.44∗∗ 2.94 ± 1.01∗∗ 1.66 ± 0.72∗∗
Airway TGF-β (cells/104μm2) 2.52 ± 0.91 12.01 ± 2.28 4.18 ± 1.06∗∗ 2.84 ± 0.84∗∗ 0.84 ± 0.41∗∗
Airway Collagen fibers (%) 5.78 ± 0.73 16.48 ± 0.78 3.72 ± 0.44∗∗ 3.45 ± 0.66∗∗ 5.82 ± 0.48∗∗
Airway Decorin (%) 0.41 ± 0.12 5.53 ± 2.53 0.58 ± 0.19∗∗ 1.54 ± 0.31∗∗ 1.55 ± 0.23∗∗
Airway Fibronectin (%) 0.45 ± 0.08 1.0 ± 0.18 0.21 ± 0.04∗∗, # 0.98 ± 0.23 0.28 ± 0.05∗∗, #
Airway Biglycan (%) 0.48 ± 0.09 1.32 ± 0.09 0.22 ± 0.05∗∗ 0.6 ± 0.11∗∗, & 0.75 ± 0.09∗∗, &

p < 0.05 compared to SAL group; ∗∗p < 0.05 compared to OVA group; #p < 0.05 compared to OVA-anti-IL17; &p < 0.05 compared to OVA-RHOi.