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. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183

Table 4.

Absolute values for remodeling markers in the alveolar septa.

Remodeling markers SAL OVA OVA-RHOi OVA-anti-IL17 OVA-RHOi-anti-IL17
Alveolar septa MMP-9 (cells/104μm2) 11.4 ± 1.25 19.78 ± 2.01 13.68 ± 1.08∗∗ 8.3 ± 0.7∗∗, & 11.28 ± 0.8∗∗
Alveolar septa MMP-12 (cells/104μm2) 2.62 ± 0.55 7.39 ± 1.08 4.7 ± 0.71∗∗ 4.16 ± 0.6∗∗ 2.83 ± 0.43∗∗
Alveolar septa TIMP-1 (cells/104μm2) 0.83 ± 0.2 8.72 ± 0.85 5.65 ± 0.61∗, ∗∗ 4.95 ± 0.61∗, ∗∗ 4.75 ± 0.72∗, ∗∗
Alveolar septa TGF-β (cells/104μm2) 3.8 ± 0.7 14.59 ± 1.7 11.16 ± 0.96∗, ∗∗ 7.95 ± 1.0∗, ∗∗ 2.62 ± 0.48∗∗, $
Alveolar septa Collagen fibers (%) 6.89 ± 0.5 12.43 ± 0.7 6.08 ± 0.35∗∗, # 4.39 ± 0.29∗, ∗∗ 7.06 ± 0.38∗, ∗∗, #
Alveolar septa Decorin (%) 5.57 ± 0.7 13.81 ± 1.05 5.28 ± 0.57∗∗ 4.03 ± 0.38∗∗ 5.06 ± 0.5∗∗
Alveolar septa Fibronectin (%) 1.38 ± 0.09 3.02 ± 1.29 0.28 ± 0.04∗, ∗∗, # 1.23 ± 0.26∗∗ 0.56 ± 0.07∗, ∗∗
Alveolar septa Biglycan (%) 1.2 ± 0.11 3.64 ± 0.29 0.18 ± 0.05∗, ∗∗ 1.54 ± 0.15∗∗, & 3.0 ± 0.26∗, ∗∗, &

p < 0.05 compared to SAL group; ∗∗p < 0.05 compared to OVA group; $p < 0.05 compared to OVA-RHOi and OVA-anti-IL17; #p < 0.05 compared to OVA-anti-IL17; &p < 0.05 compared to OVA-RHOi.