Table 3.
IgG isotypes levels of the study subjects stratified according to tertiles of insulin-stimulated glucose disposal.
| Tertile 1 | Tertile 2 | Tertile 3 | P value adjusted for age and gender | |
|---|---|---|---|---|
| Male/female | 49/38 | 52/36 | 36/51 | 0.04 |
| Age (yrs) | 38 ± 10 | 40 ± 10 | 39 ± 9 | 0.47 |
| BMI (kg/m2) | 32.1 ± 6.4 | 30.4 ± 5.2 | 27.5 ± 6.1 | <0.0001 |
| Total IgG (mg/ml) | 11.4 ± 2.5 | 11.4 ± 2.7 | 11.2 ± 2.5 | 0.87 |
| IgG1 (mg/ml) | 6.4 ± 1.6 | 6.5 ± 1.6 | 6.5 ± 1.8 | 0.79 |
| IgG2 (mg/ml) | 4.2 ± 1.5 | 4.0 ± 1.6 | 3.7 ± 1.3 | 0.04 |
| IgG3 (mg/ml) | 0.39 ± 0.21 | 0.41 ± 0.20 | 0.39 ± 0.18 | 0.75 |
| IgG4 (mg/ml) | 0.53 ± 0.06 | 0.69 ± 0.07 | 0.49 ± 0.05 | 0.42 |
| Insulin-stimulated glucose disposal (mg * min−1 * kg FFM −1) | 3.4 ± 0.9 | 6.5 ± 0.8 | 11.2 ± 3.0 | <0.0001 |
Data are means ± SD. Comparisons between the three groups were performed using a general linear model for multiple comparisons. BMI = body mass index.