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. 2018 Sep 11;8:13641. doi: 10.1038/s41598-018-31804-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of restricting food access to the normal rest phase in published experimental data (pancreas, mouse)^18,19. (A) Measurement of the feeding activity which corresponds to the number of pellets consumed per hour¹⁹. (B,C) Levels of blood glucose and insulin¹⁸. (D–F) Pancreatic clock gene expression¹⁸. Comparison between the normal feeding (in blue) and the time-restricted feeding (in red) conditions. The alternation of white and grey bars symbolises the LD cycles.