Table 4.
Multivariable analysis for PFS for patients receiving a transplant and for all patients who had a MUD search
| Measure | HR (95% CI) | P |
|---|---|---|
| Multivariable analysis for PFS for patients receiving a transplant, N = 151 | ||
| Donor | ||
| Related (MRD/Haplotype) vs 10/10 MUD and 9/10 MUD | 1.20 (0.62-2.33) | .50 |
| Disease status at transplant | ||
| CR1/2 vs other | 0.63 (0.37-1.08) | .09 |
| Cytogenetics | ||
| Adverse vs intermediate/favorable | 3.18 (1.87-5.43) | <.0001 |
| Diagnosis | ||
| De novo AML vs other | 0.39 (0.19-0.79) | .009 |
| Time from MUD search to transplant, continuous | 1.00 (1.00-1.01) | .010 |
| Multivariable analysis for PFS for all patients who had a MUD search, N = 242 | ||
| Race | ||
| White vs other | 0.98 (0.66-1.46) | .92 |
| Disease status at MUD search | ||
| Remission/newly diagnosed vs other | 0.52 (0.36-0.74) | <.001 |
| Cytogenetics | ||
| Adverse vs intermediate/favorable | 2.67 (1.87-3.83) | <.0001 |
| Diagnosis | ||
| De novo AML vs other | 0.40 (0.26-0.63) | <.0001 |
| Haplotype frequency | ||
| Common vs uncommon | 0.68 (0.45-1.02) | .06 |
| Transplant | ||
| Yes vs no | 0.32 (0.23-0.45) | <.0001 |