Table 1.
Variables | Supine position | Prone position | P values | N* | ||||
---|---|---|---|---|---|---|---|---|
PEEP/FIO2 table | Pes-guided strategy | PEEP/FIO2 table | Pes-guided strategy | Position effect | PEEP strategy effect | Position and PEEP interaction | ||
PEEP set on ventilator (cmH2O) | 10 ± 2 | 12 ± 4 | 10 ± 2 | 12 ± 5 | 0.96 | 0.05 | 0.96 | 37 |
Paw,ee (cmH2O) | 11 ± 3 | 13 ± 4 | 11 ± 3 | 13 ± 5 | 0.47 | 0.05 | 0.91 | 37 |
Paw,ei (cmH2O) | 23 ± 4 | 24 ± 6 | 22 ± 4 | 24 ± 6 | 0.11 | 0.08 | 0.78 | 37 |
Pes,ee (cmH2O) | 9 ± 4 | 10 ± 5 | 9 ± 4 | 10 ± 5 | 0.88 | 0.05 | 0.83 | 37 |
Pes,ei (cmH2O) | 12 ± 4 | 14 ± 5 | 13 ± 4 | 14 ± 6 | 0.66 | 0.01 | 0.80 | 37 |
Pga,ee (cmH2O) | 12 ± 6 | 12 ± 5 | 18 ± 6 | 18 ± 7 | < 0.001 | 0.19 | 0.06 | 31 |
Pga,ei (cmH2O) | 14 ± 6 | 14 ± 6 | 20 ± 6 | 21 ± 7 | < 0.001 | 0.11 | 0.04 | 31 |
PL,ee (cmH2O) | 2 ± 3 | 2 ± 2 | 2 ± 3 | 3 ± 2 | 0.78 | 0.15 | 0.96 | 37 |
PL,ei (cmH2O) | 10 ± 5 | 11 ± 5 | 10 ± 5 | 10 ± 4 | 0.03 | 0.47 | 0.66 | 37 |
PL,ei_Elastance (cmH2O) | 16 ± 5 | 17 ± 6 | 15 ± 5 | 15 ± 6 | < 0.01 | 0.46 | 0.34 | 37 |
DPrs (cmH2O) | 12 ± 4 | 12 ± 4 | 11 ± 3 | 11 ± 4 | < 0.001 | 0.88 | 0.65 | 37 |
DPcw (cmH2O) | 3 ± 1 | 3 ± 2 | 3 ± 1 | 4 ± 1 | 0.33 | 0.03 | 0.42 | 37 |
DPL (cmH2O) | 9 ± 4 | 8 ± 4 | 8 ± 4 | 7 ± 4 | < 0.001 | 0.34 | 0.38 | 37 |
Est,rs (cmH2O/L) | 34 ± 14 | 35 ± 14 | 32 ± 14 | 33 ± 14 | 0.04 | 0.46 | 0.83 | 37 |
Est,cw (cmH2O/L) | 9 ± 4 | 10 ± 5 | 10 ± 3 | 11 ± 4 | 0.22 | 0.01 | 0.30 | 37 |
Est,L (cmH2O/L) | 25 ± 15 | 25 ± 15 | 22 ± 15 | 22 ± 15 | 0.01 | 0.71 | 0.64 | 37 |
PaCO2 (mmHg) | 53 ± 16 | 55 ± 17 | 52 ± 14 | 52 ± 18 | 0.08 | 0.12 | 0.36 | 36 |
PaO2/FIO2 ratio (mmHg) | 143 ± 28 | 149 ± 31 | 172 ± 51 | 187 ± 53 | < 0.001 | 0.03 | 0.17 | 36 |
EELV (mL) | 1359 ± 503 | 1427 ± 456 | 1266 ± 391 | 1328 ± 415 | 0.01 | 0.08 | 0.93 | 37 |
Values are mean ± SD
PEEP positive end-expiratory pressure, Paw,ee static end-expiratory pressure of the respiratory system, Paw,ei static end-inspiratory pressure of the respiratory system, Pes,ee static end-expiratory esophageal pressure, Pes,ei static end-inspiratory esophageal pressure, Pga,ee static end-expiratory gastric pressure, Pga,ei static end-inspiratory gastric pressure, PL,ee static end-expiratory transpulmonary pressure, PL,ei static end-inspiratory transpulmonary pressure, PL,ei _Elastance Paw,ei × Est,L/Est,rs, Est,rs, Est,cw, Est,L static elastance, of respiratory system, chest wall and lung, respectively, DPrs, DPcw, DPL driving pressure of respiratory system, chest wall and lung, respectively, EELV end-expiratory lung volume
*Due to incomplete data, some patients were excluded from the analysis