Table 2.
Characteristics of the study participants divided by first-trimester TSH concentrationa
| Characteristics | Normal (n = 1532) |
eTSH (2.5–4 mIU/L) (n = 142) |
P |
|---|---|---|---|
| Maternal age (years) | 30 (27–34) | 29 (28–32) | 0.35 |
| Pregestational BMI (kg/m2) | 20.03 (18.83–21.68) | 19.32 (±1.91) | 0.01 |
| Gestational age at delivery (weeks) | 39.29 (38.57–40.00) | 39.14 (38.57–40.00) | 0.83 |
| Postpartum hemorrhage volume (ml) | 305 (255–380) | 317 (260–380) | 0.41 |
| Neonatal birth weight (kg) | 3.20 (2.95–3.50) | 3.27 (±0.41) | 0.05 |
| TSH (mIU/L) | 1.06 (0.67–1.54) | 3.06 (2.76–3.40) | < 0.001 |
| FT4 (pmol/L) | 16.46 (±3.11) | 15.82 (±2.74) | 0.02 |
| Blood glucose on 75-g OGTT (mmol/L) | |||
| 0 h | 4.12 (3.94–4.36) | 4.13 (3.92–4.31) | 0.42 |
| 1 h | 7.30 (6.16–8.46) | 6.64 (5.70–7.86) | < 0.001 |
| 2 h | 6.45 (5.64–7.36) | 6.31 (5.58–7.01) | 0.12 |
aValues are mean (SD) or median (interquartile range)
TSH thyroid-stimulating hormone, eTSH elevated thyroid-stimulating hormone, BMI body mass index, FT4 free thyroxine 4, OGTT oral glucose tolerance test