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. 2018 Aug 10;12(5):937–952. doi: 10.1177/1932296818788873

Table 1.

Model Parameters With Population Values for SOGMM.

Symbol Meaning Value Range Units
Sg Fractional glucose effectiveness 0.01 [0,0.1] 1/min
Vg Distribution volume of glucose 1.6 Fixed dl/kg
kabs Rate constant—oral glucose consumption 0.01193 Fixed 1/min
kτ Time constant related with oral glucose absorption 0.08930 Fixed 1/min
p2 Rate constant of the remote insulin compartment 0.02 Fixed 1/min
f Fraction of intestinal absorption 0.9 Fixed
VI Distribution volume of insulin 0.06005 [0,5] 1/kg
kcl Rate constant of subcutaneous insulin transport 0.16 [0,0.1] 1/min
kd Rate constant of subcutaneous insulin transport 0.02 [0,0.1] 1/min
SI Insulin sensitivity 0.0006 [0.5×104,12×104] 1/min/mU/l
BW Body weight Known Fixed kg
Gb Basal glucose concentration Eq. (2) Fixed mg/dl
Ib Reference value for I(t), associated with the fasting plasma glucose concentration. Steady-state Fixed mU/l