Table 1.
Model Parameters With Population Values for SOGMM.
Symbol | Meaning | Value | Range | Units |
---|---|---|---|---|
Fractional glucose effectiveness | 0.01 | 1/min | ||
Distribution volume of glucose | 1.6 | Fixed | dl/kg | |
Rate constant—oral glucose consumption | 0.01193 | Fixed | 1/min | |
Time constant related with oral glucose absorption | 0.08930 | Fixed | 1/min | |
Rate constant of the remote insulin compartment | 0.02 | Fixed | 1/min | |
Fraction of intestinal absorption | 0.9 | Fixed | — | |
Distribution volume of insulin | 0.06005 | 1/kg | ||
Rate constant of subcutaneous insulin transport | 0.16 | 1/min | ||
Rate constant of subcutaneous insulin transport | 0.02 | 1/min | ||
Insulin sensitivity | 0.0006 | 1/min/mU/l | ||
Body weight | Known | Fixed | kg | |
Basal glucose concentration | Eq. (2) | Fixed | mg/dl | |
Reference value for , associated with the fasting plasma glucose concentration. | Steady-state | Fixed | mU/l |