Table 1.
Baseline characteristics and laboratory data of the patients and controls
| HBOT group (n = 25) | Disease controls (n = 25) | p value | |
|---|---|---|---|
| Age, years | 61.3 ± 8.7 | 62.7 ± 12.5 | 0.679 |
| Sex (female:male) | 15:10 | 14:11 | 0.774 |
| Body mass index | 24.7 ± 2.9 | 23.9 ± 4.1 | 0.455 |
| NIHSS at enrollment | 7.4 ± 3.2 | 6.4 ± 2.5 | 0.301 |
| Mean systolic blood pressure (mmHg) | 142.2 ± 12.1 | 149.7 ± 25.5 | 0.202 |
| Mean diastolic blood pressure (mmHg) | 89.5 ± 11.6 | 82.2 ± 18.4 | 0.102 |
| Underlying diseases | |||
| Hypertension, n (%) | 14 (56%) | 11 (44%) | 0.396 |
| Diabetes mellitus, n (%) | 11 (50%) | 11 (50%) | 1.0 |
| Dyslipidemia, n (%) | 3 (38%) | 5 (62%) | 0.44 |
| Peripheral blood studies | |||
| White blood cells (×103/mL) | 8.0 ± 2.2 | 7.9 ± 2.3 | 0.882 |
| Hemoglobin | 14.3 ± 1.72 | 12.8 ± 1.6 | 0.008 |
| Hematocrit | 42.2 ± 4.8 | 38.7 ± 4.5 | 0.019 |
| APTT | 27.7 ± 2.5 | 26.9 ± 3.5 | 0.397 |
| PT | 10.5 ± 0.5 | 10.3 ± 0.6 | 0.262 |
| Platelet count (×104/mL) | 236.7 ± 61.4 | 242.8 ± 45.2 | 0.718 |
| Total cholesterol, mg/dL | 207.3 ± 73.1 | 171.6 ± 44.0 | 0.062 |
| HDL-C, mg/dL | 44.0 ± 15.0 | 42.6 ± 12.7 | 0.749 |
| LDL-C, mg/dL | 126.5 ± 64.2 | 99.5 ± 39.5 | 0.108 |
| Triglyceride, mg/dL | 147.4 ± 72.0 | 132.9 ± 94.7 | 0.58 |
| HbA1c | 8.2 ± 2.6 | 7.3 ± 2.1 | 0.250 |
| Ca | 9.3 ± 0.43 | 9.0 ± 0.44 | 0.041 |
| Hs-CRP, mg/L | 5.1 ± 3.2 | 4.1 ± 2.8 | 0.428 |
Values are expressed as mean ± SD unless otherwise indicated
HBOT hyperbaric oxygen therapy, HBA1c glycosylated hemoglobin, aPTT activated partial thromboplastin time, PT prothrombin time, hs-CRP high-sensitivity C-reactive protein, NIHSS National Institutes of Health Stroke Scale