Table 2.
Subgroup CVD risk factor characteristics
| Subgroups | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
|---|---|---|---|---|---|---|---|---|---|
| N | 103 | 20 | 29 | 339 | 22 | 21 | 207 | 229 | 479 |
| Events (%) | 16 (15.5) | 1 (5.0) | 0 (0.0) | 14 (4.1) | 9 (40.9) | 2 (9.5) | 22 (10.6) | 43 (18.8) | 94 (19.6) |
| Male sex (%) | 45 (43.7) | 8 (40.0) | 16 (55.2) | 170 (50.1) | 16 (72.7) | 10 (47.6) | 0 (0.0) | 229 (100.0) | 247 (51.6) |
| Age (years) | 64.4 [59.9, 66.3] | 60.0 [53.5, 62.7] | 62.2 [57.3, 66.0] | 62.0 [57.8, 65.3] | 66.0 [63.6, 68.3] | 63.3 [62.1, 66.2] | 63.1 [58.5, 65.7] | 63.3 [59.6, 66.0] | 72.5 [70.6, 75.0] |
| Smoking (% yes) | 13 (12.6) | 2 (10.0) | 6 (20.7) | 34 (10.0) | 4 (18.2) | 1 (4.8) | 44 (21.3) | 61 (26.6) | 62 (12.9) |
| Employed (% yes) | 56 (54.4) | 15 (75.0) | 15 (51.7) | 200 (59.0) | 9 (40.9) | 11 (52.4) | 86 (41.5) | 141 (61.6) | 68 (14.2) |
| Body mass index (kg/m2) | 26.1 [23.3, 28.9] | 23.3 [22.0, 25.8] | 24.5 [22.6, 27.3] | 26.2 [23.6, 29.3] | 29.2 [26.0, 30.7] | 27.8 [25.0, 31.0] | 29.0 [25.4, 33,0] | 29.1 [26.7, 31.7] | 26.5 [24.2, 29.5] |
| Systolic blood pressure (mmHg) | 129 (14) | 127 (15) | 130 (14) | 127 (14) | 167 (8) | 167 (12) | 131 (17) | 137 (16.3) | 135 (17.0) |
| Diastolic blood pressure (mmHg) | 81 (9) | 79 (11) | 82 (9) | 81 (9) | 100 (6) | 95 (11) | 83.2 (9.8) | 84.6 (10.1) | 80.1 (10.3) |
| Total cholesterol (mmol/l) | 5.7 (0.8) | 5.4 (0.7) | 5.8 (1.0) | 5.4 (1.0) | 5.8 (0.9) | 6.0 (1.0) | 5.3 (1.0) | 5.1 (1.0) | 5.3 (1.1) |
| High density lipoprotein cholesterol (mmol/l) | 1.5 [1.2, 2.0] | 1.5 [1.4, 2.2] | 1.7 [1.4, 2.0] | 1.6 [1.3, 1.8] | 1.3 [1.0, 1.2] | 1.5 [1.4, 2.2] | 1.5 [1.1, 1.8] | 1.1 [1.0, 1.5] | 1.6 [1.2, 1.8] |
| Low density lipoprotein cholesterol (mmol/l) | 3.3 (0.7) | 3.1 (0.5) | 3.5 (0.9) | 3.4 (0.9) | 3.7 (0.7) | 3.6 (0.6) | 3.2 (1.0) | 3.1 (1.1) | 3.3 (1.0) |
| Triacylglycerol (mmol/l) | 1.0 [0.9, 1.3] | 0.7 [0.5, 1.3] | 1.1 [0.6, 1.5] | 1.0 [0.8, 1.3] | 1.5 [1.1, 2.3] | 0.8 [0.7, 1.0] | 1.2 [1.0, 1.8] | 1.4 [1.1, 2.1] | 1.1 [0.7, 1.5] |
| HbA1c (%) | 5.3 [5.3, 5.5] | 5.4 [5.4, 5.5] | 5.4 [5.3, 5.6] | 5.4 [5.2, 5.5] | 5.6 [5.3, 5.6] | 5.4 [5.4, 5.5] | 6.0 [5.7, 6.1] | 6.0 [5.8, 6.3] | 5.8 [5.4, 6.0] |
| Albumin creatinine ratio | 29 (20) | 38.3 (16.7) | 27.5 (19.6) | 105.6 (21.0) | 76.0 (44.0) | 74.2 (43.2) | 77.2 (46.4) | 84.3 (40.1) | 79.2 (43.3) |
| Estimated glomerular filtration rate (ml/min/1.73m2) | 80.0 [72.0, 89.0] | 74.0 [70.8, 75.4] | 88.0 [84.0, 93.0] | 81.0 [72.0, 89.0] | 77.4 [69.3, 88.0] | 78.0 [73.0, 89.0] | 82.0 [71.0, 91.4] | 86.0 [76.0, 92.0] | 74.0 [66.0, 84.0] |
| Any anti-diabetic drug (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 6 (1.8) | 1 (4.5) | 0 (0.0) | 22 (10.8) | 26 (11.4) | 18 (3.8) |
| Any anti-hypertensive drug (%) | 38 (36.9) | 5 (25.0) | 4 (13.8) | 98 (29.3) | 9 (40.9) | 10 (47.6) | 98 (48.0) | 96 (41.9) | 216 (45.5) |
| Any lipid-lowering drug (%) | 15 (14.6) | 2 (10.0) | 2 (6.9) | 39 (11.6) | 4 (18.2) | 1 (4.8) | 80 (39.2) | 81 (35.4) | 134 (28.2) |
| Aspirin (%) | 9 (8.7) | 0 (0.0) | 1 (3.4) | 26 (7.8) | 4 (18.2) | 5 (23.8) | 36 (17.6) | 43 (18.8) | 85 (17.9) |
Data are median [IQR], mean (SD) or n (%)
HbA1c glycated hemoglobin A1c
* For p-value < 0.05 and ** for < 0.01
aEmployed includes the self-employed. Out of work includes the unemployed, housewives, retired individuals and individuals receiving government provisions