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. 2018 Sep 12;19:322. doi: 10.1186/s12859-018-2344-6

Table 2.

Variables selected by priority-Lasso in scenarios pl2A and pl2B

Block Variable Coef. pl2A Coef. pl2B
1 t(8;21)(q22;q22) -1.0289 -1.0289
inv(16)(p13.1q22) -1.5444 -1.5444
NPM1 mut/FLT3-ITD neg or low -1.0181 -1.0181
biCEBPA -1.2240 -1.2240
NPM1 wt/FLT3-ITD pos or low -0.4358 -0.4358
t(9;11)(p21;q23) 0.4635 0.4635
Other aberrations -0.4376 -0.4376
KMT2A rearrangements -0.5440 -0.5440
Complex karyotype 0.2970 0.2970
Monosomal karyotype 0.0313 0.0313
NPM1 wt/FLT3-ITD pos 0.1712 0.1712
RUNX1 mutations 0.3065 0.3065
ASXL mutations -0.1224 -0.1224
TP53 mutations 0.4306 0.4306
2 Age 0.2957 0.2617
Sex -0.1011
ECOG (> 1) 0.3147 0.3206
WBC 0.0990 0.0589
LDH 0.1681 0.2371
Hb 0.0700 0.0671
PLT -0.0960 -0.0578
4 ZBTB37 0.0047 0.0025
MFI2 0.0090
SH3PXD2B 0.0013 0.0418
PDK3 -0.0187
FAM24B 0.0248
SIK3 -0.0063
OR7A17 0.0039
TBC1D17 -0.0172
PHGDH 0.0488
FAM171B 0.0134
FGD5 0.0359
F12 0.0238
IRX1 -0.0090
FAM92A1 0.0239
DDIT4 0.0769
HSPA2 0.0169

Column 1: priority of the block the variable is included in. Column 2: variable name. Column 3 and 4: coefficient of the variable in the Cox Lasso model. Variables from the block of priority 4 also appearing in Table 1 are marked in bold