Table 2.
Block | Variable | Coef. pl2A | Coef. pl2B |
---|---|---|---|
1 | t(8;21)(q22;q22) | -1.0289 | -1.0289 |
inv(16)(p13.1q22) | -1.5444 | -1.5444 | |
NPM1 mut/FLT3-ITD neg or low | -1.0181 | -1.0181 | |
biCEBPA | -1.2240 | -1.2240 | |
NPM1 wt/FLT3-ITD pos or low | -0.4358 | -0.4358 | |
t(9;11)(p21;q23) | 0.4635 | 0.4635 | |
Other aberrations | -0.4376 | -0.4376 | |
KMT2A rearrangements | -0.5440 | -0.5440 | |
Complex karyotype | 0.2970 | 0.2970 | |
Monosomal karyotype | 0.0313 | 0.0313 | |
NPM1 wt/FLT3-ITD pos | 0.1712 | 0.1712 | |
RUNX1 mutations | 0.3065 | 0.3065 | |
ASXL mutations | -0.1224 | -0.1224 | |
TP53 mutations | 0.4306 | 0.4306 | |
2 | Age | 0.2957 | 0.2617 |
Sex | -0.1011 | ||
ECOG (> 1) | 0.3147 | 0.3206 | |
WBC | 0.0990 | 0.0589 | |
LDH | 0.1681 | 0.2371 | |
Hb | 0.0700 | 0.0671 | |
PLT | -0.0960 | -0.0578 | |
4 | ZBTB37 | 0.0047 | 0.0025 |
MFI2 | 0.0090 | ||
SH3PXD2B | 0.0013 | 0.0418 | |
PDK3 | -0.0187 | ||
FAM24B | 0.0248 | ||
SIK3 | -0.0063 | ||
OR7A17 | 0.0039 | ||
TBC1D17 | -0.0172 | ||
PHGDH | 0.0488 | ||
FAM171B | 0.0134 | ||
FGD5 | 0.0359 | ||
F12 | 0.0238 | ||
IRX1 | -0.0090 | ||
FAM92A1 | 0.0239 | ||
DDIT4 | 0.0769 | ||
HSPA2 | 0.0169 |
Column 1: priority of the block the variable is included in. Column 2: variable name. Column 3 and 4: coefficient of the variable in the Cox Lasso model. Variables from the block of priority 4 also appearing in Table 1 are marked in bold