Table 1.
Significant enriched GO terms of up-regulated DEGs in ovarian cancer
| Term name | Description | Count | p-value |
|---|---|---|---|
| Enrichment Score: 2.46 | |||
| GO:0048248 | CXCR3 chemokine receptor binding | 4 | 1.49E-05 |
| GO:0006955 | immune response | 17 | 2.97E-05 |
| GO:0070098 | chemokine-mediated signaling pathway | 7 | 1.64E-04 |
| GO:0008009 | chemokine activity | 6 | 2.47E-04 |
| GO:0030816 | positive regulation of cAMP metabolic process | 3 | 0.00191 |
| GO:0043950 | positive regulation of cAMP-mediated signaling | 3 | 0.00804 |
| GO:0007267 | cell-cell signaling | 9 | 0.00918 |
| GO:0006935 | chemotaxis | 6 | 0.01338 |
| GO:0002690 | positive regulation of leukocyte chemotaxis | 3 | 0.01781 |
| GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | 3 | 0.03821 |
| GO:0032496 | response to lipopolysaccharide | 6 | 0.04135 |
| Enrichment Score: 2.06 | |||
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 12 | 9.65E-05 |
| GO:0043565 | sequence-specific DNA binding | 17 | 3.48E-04 |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 22 | 0.00447 |
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 11 | 0.00836 |
| GO:0006366 | transcription from RNA polymerase II promoter | 13 | 0.01569 |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | 17 | 0.09053 |