Table 1.
Variable | n | EphA2 | miR302b | |||||
---|---|---|---|---|---|---|---|---|
High | Low | P | High | Low | P | |||
Age (years) | ||||||||
<60 | 123 | 89 | 34 | 0.684 | 54 | 69 | 0.128 | |
≧60 | 103 | 77 | 26 | 35 | 68 | |||
Gender | ||||||||
Male | 113 | 86 | 27 | 0.366 | 45 | 68 | 0.892 | |
Female | 113 | 80 | 33 | 44 | 69 | |||
Primary tumor location | ||||||||
Fundus and cardia | 110 | 85 | 25 | 0.205 | 37 | 73 | 0.085 | |
Distal third | 116 | 81 | 35 | 52 | 64 | |||
Lauren's | ||||||||
Diffuse | 131 | 94 | 37 | 0.498 | 47 | 84 | 0.206 | |
Intestinal | 95 | 72 | 23 | 42 | 53 | |||
Depth of invasion | ||||||||
T1 | 22 | 12 | 10 | 0.036 | 15 | 7 | 0.003 | |
T2 | 55 | 37 | 18 | 27 | 28 | |||
T3 | 118 | 90 | 28 | 39 | 79 | |||
T4 | 31 | 27 | 4 | 8 | 23 | |||
Lymph node metastasis | ||||||||
Positive | 136 | 110 | 26 | 0.002 | 43 | 93 | 0.003 | |
Negative | 90 | 56 | 34 | 46 | 44 | |||
TNM stage | ||||||||
I | 23 | 10 | 13 | <0.001 | 16 | 7 | <0.001 | |
II | 52 | 33 | 19 | 31 | 21 | |||
III | 67 | 52 | 15 | 19 | 48 | |||
IV | 84 | 71 | 13 | 23 | 61 | |||
Lymphatic invasion | ||||||||
Yes | 97 | 77 | 20 | 0.002 | 32 | 65 | 0.001 | |
No | 81 | 47 | 34 | 46 | 35 | |||
Venous invasion | ||||||||
Yes | 56 | 43 | 13 | 0.161 | 22 | 34 | 0.409 | |
No | 122 | 81 | 41 | 56 | 66 |