Table 5.

Annual Changes in Renal Function, Albuminuria, Glycemic Control, and Lipid Indices Before and After First DRC Attendance, Stratified by CKD Etiology^a

Variable	Type 1 diabetes mellitus			Type 2 diabetes mellitus			Additional CKD etiology
	Before DRC	After DRC	P value	Before DRC	After DRC	P value	Before DRC	After DRC	P value
Absolute change in renal function (mL/min/body surface area/year)	(n=34)	(n=43)		(n=115)	(n=125)		(n=28)	(n=30)
Modification of Diet in Renal Disease eGFR	−1.14b	−3.52	.10	−5.56	−3.31	.01	−6.40	0.68c	<.001
Chronic Kidney Disease Epidemiology Collaboration eGFR	−1.59	−3.10	.31	−5.64	−3.07	.004	−6.50	0.91	<.001
Percentage change in renal function (%/year)
Modification of Diet in Renal Disease eGFR	−0.95	−9.87	.04	−10.44	−10.06	.87	−12.82	1.95	.001
Chronic Kidney Disease Epidemiology Collaboration eGFR	−1.22	−9.39	.06	−10.88	−9.94	.70	−13.28	−2.29	.001
	(n=41)	(n=42)		(n=117)	(n=123)		(n=28)	(n=30)
Absolute change in urine albumin to creatinine ratio (mg/g/year)	−4.42	−2.12	.97	75.49	52.57	.48	−28.23	−50.00	.73
	(n=42)	(n=42)		(n=120)	(n=123)		(n=29)	(n=30)
Absolute change in International Federation of Clinical Chemistry glycated hemoglobin (mmol/mol/year)	−2.66	−1.30	.09	−1.26	0.25	.003	−0.89	−0.37	.60
	(n=41)	(n=40)		(n=119)	(n=110)		(n=27)	(n=27)
Absolute change in non–LDL-C lipid indices (mg/dL/year)
Total cholesterol	0.00	−5.03	.005	−1.16	−1.55	.85	−1.16	−1.55	.84
High-density lipoprotein cholesterol	0.00	−0.77	.07	−0.77	−0.39	.06	−0.77	−0.39	.47
Triglycerides	0.00	−7.97	.09	0.00	−2.66	.40	2.66	−2.66	.33
	(n=41)	(n=40)		(n=115)d	(n=107)d		(n=27)	(n=27)
Absolute change in LDL-C (mg/dL/year)	−0.39	−2.32	.16	−0.39	−0.77	.59	−0.39	−0.39	.86

^aCKD = chronic kidney disease; DRC = diabetes renal clinic; eGFR = estimated glomerular filtration rate; LDL-C = low-density lipoprotein cholesterol.

^bNegative integers represent an annual decline in laboratory indices.

^cPositive integers represent an annual increase in laboratory indices.

^dLDL C values were calculated using the Friedwald equation. LDL-C values were not calculated for individuals with triglyceride readings >400 mg/dL, hence the lower number of individuals included in LDL-C analyses compared with non–LDL-C lipid analyses.