Table 7.
Biological processes for up-regulated genes in cADSCs compared to ADRCs.
| Networks | Total gees | p-Value | FDR | Genes in data | Network objects from active data |
|---|---|---|---|---|---|
| Development_Cartilage development | 66 | 7.01E−05 | 0.006166 | 6 | Fibronectin, VDR, ROR2, Activin beta A, RUNX2, Fibrillin |
| Development_Neurogenesis in general | 192 | 0.000202 | 0.008844 | 9 | Frizzled, Galpha(q)-specific amine GPCRs, FZD2, Adenosine A1 receptor, Activin beta A, SERPINE2, WNT, GDNF, ARNT2 |
| Reproduction_FSH-beta signaling pathway | 160 | 0.000301 | 0.008844 | 8 | PSG13, SCCA-1, PSG-5, ROR2, Activin beta A, PSG6, PSG1, PSG11 |
| Cell adhesion_Cell-matrix interactions | 211 | 0.000408 | 0.008969 | 9 | Fibronectin, Tenascin-C, MMP-1, Stromelysin-1, Fibrillin 2, Layilin, Fibrillin, LAMA1, Thrombospondin 1 |
| Development_Ossification and bone remodeling | 157 | 0.001436 | 0.025274 | 7 | Frizzled, Activin, HOXC8, RUNX2, Osteoprotegerin, Cadherin 11, WNT |
| Proteolysis_Connective tissue degradation | 119 | 0.008978 | 0.124094 | 5 | Fibronectin, Tenascin-C, SERPINE2, MMP-1, Stromelysin-1 |
| Development_Neurogenesis_Synaptogenesis | 180 | 0.012735 | 0.124094 | 6 | Frizzled, Nav1.6, Liprin-alpha4, Thrombospondin 1, WNT, Thrombospondin 2 |
| Cell adhesion_Cadherins | 180 | 0.012735 | 0.124094 | 6 | SSX2IP, Frizzled, STMN2, DKK1, Cadherin 11, WNT |
| Proteolysis_ECM remodeling | 85 | 0.013084 | 0.124094 | 4 | Fibronectin, Tenascin-C, MMP-1, Stromelysin-1 |
| Inflammation_IL-13 signaling pathway | 91 | 0.016458 | 0.124094 | 4 | Tenascin-C, IL13RA2, SCCA-1, SCCA-2 |
| Signal Transduction_BMP and GDF signaling | 91 | 0.016458 | 0.124094 | 4 | Gremlin, ROR2, HOXC8, RUNX2 |
| Cell adhesion_Amyloid proteins | 195 | 0.018264 | 0.124094 | 6 | Fibronectin, Frizzled, FZD2, F-spondin, WNT5B, WNT |
| Blood coagulation | 94 | 0.018332 | 0.124094 | 4 | SERPINE2, MMP-1, PAR3, Thrombospondin 1 |
| Cardiac development_Wnt_beta-catenin, Notch, VEGF, IP3 and integrin signaling | 150 | 0.022508 | 0.141479 | 5 | Frizzled, SALL4, DKK1, Thrombospondin 1, WNT |
| Reproduction_Progesterone signaling | 214 | 0.027392 | 0.160698 | 6 | Fibronectin, Frizzled, KIBRA, Galpha(q)-specific peptide GPCRs, WNT, Pitx2 |
| Signal transduction_WNT signaling | 177 | 0.041679 | 0.229236 | 5 | Fibronectin, Frizzled, FZD2, WNT5B, WNT |
| Neurophysiological process_Transmission of nerve impulse | 212 | 0.077966 | 0.393232 | 5 | HTR2A, Glycine receptor beta chain, MaxiK alpha subunit, GluR3, Serotonin receptor |
| Cell adhesion_Integrin-mediated cell-matrix adhesion | 214 | 0.080434 | 0.393232 | 5 | Fibronectin, Tubulin beta 3, Tenascin-C, Tubulin beta, TM4SF9 |
| Muscle contraction | 173 | 0.115956 | 0.518155 | 4 | Galpha(q)-specific amine GPCRs, MaxiK alpha subunit, Galpha(q)-specific peptide GPCRs, Thrombospondin 1 |
| Cell adhesion_Platelet-endothelium-leucocyte interactions | 174 | 0.117762 | 0.518155 | 4 | Fibronectin, SERPINE2, Thrombospondin 1, Thrombospondin 2 |