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. 2017 Apr 27;1(1):111–116. doi: 10.1016/j.mayocpiqo.2017.04.003

Figure 2.

Figure 2

Identification of STRN-ALK fusion in the patient’s paraffin-embedded surgical samples. A, Paired-end sequencing data from tumor tissue samples indicated somatic intrachromosomal STRN-ALK fusion as demonstrated by Integrative Genomics Viewer program. B, Confirmation of the STRN-ALK fusion by polymerase chain reaction. The expected product size is 166 bp. C, DNA sequence chromatograms show the conjoined regions at the DNA sequence level of the STRN-ALK fusion gene. D, Schematic diagram of the predicted domains of the STRN-ALK fusion protein. M = marker (100-bp ladder); NC = negative control; P = paraffin-embedded tissue sample.