Table 1.
Clinical and demographic data including follow-up data of the patients. Four of the RRMS patients had transitioned to SPMS, one of whom was deceased.
| Cohort | Controls | RRMS | SPMS |
|---|---|---|---|
| n | 10 | 30 | 16 |
| On treatment, n | 0 | 15 | 1 |
| Age, mean(±SD) | 39(±13.1) | 39(±10.6) | 58(±9.3) |
| Female/Male | 6/4 | 21/9 | 10/6 |
| EDSS, median(range) | n/a | 2.0(0-7.5) | 5.5(3.0-7.5) |
| Disease duration in months, mean(±SD) | n/a | 115(±103.8) | 281(±128.3) |
| Follow-up | RRMS | SPMS | |
| n | 27 | 13 | |
| ΔEDSS, median(range) | 0.0(-3.5-3.0) | 1.5(0-4.0) | |
| Time interval in months, mean(±SD) | 68(±15.4) | 55(±18.6) | |
| Transitioned, n | 4 | n/a | |
| Deceased, n | 1 | 0 |
EDSS: expanded disability status scale; n/a: not applicable; RRMS: relapsing-remitting multiple sclerosis; SD: standard deviation; SPMS: secondary progressive multiple sclerosis.