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Roles of AMPK in ischemic stroke. A. AMPK inhibits neuroinflammation in ischemic stroke B. AMPK suppresses the levels of oxidative stress in ischemic stroke. C. AMPK promotes autophagy against ischemic stroke. D. AMPK restrains glutamate release and excitotoxicity. E. AMPK ameliorates mitochondrial dysfunction against ischemic stroke. F. AMPK inhibits apoptosis in ischemic stroke. In short, AMPK helps to main the energy homeostasis via regulating the mechanisms above.
