Methodology |
Retrospective multicentric cohort |
Retrospective single center |
Danish cohort study from 1977 to 1992 |
Population-based cohort study from 2000 to 2010 |
Study of origin |
Spain |
Germany |
Denmark |
Taiwan |
Number of patients |
5,073 IBD patients |
852 CD patients |
15,526 IBD patients, 3,538 CD patients, 11,215 UC patients, 773 indeterminate colitis (IC) patients |
11,909 IBD patients |
Type of IBD |
|
|
|
|
Follow-up period |
14 years |
10 years |
112,824 person-years |
5.33 ± 3.79 years |
Episodes of acute pancreatitis |
82 |
12 |
86 |
202 |
Incidence of acute pancreatitis |
1.6% |
1.4% |
CD patients: 4.3%, UC patients: 2.1%, IC patients: 7.1% |
31.8 per 100,000 person-years |
Number of patients with acute pancreatitis (CD/UC) |
67 patients (53 CD/14 UC) |
12 CD patients |
86 (28 CD/50 UC/8 IC) |
202 patients (128 CD/74 UC) |
Age of patients with acute pancreatitis |
40 ± 12 years (mean ± standard deviation) |
Median 23 (10 - 50) |
Unknown |
Unknown |
Etiology |
63.4% drug-induced, 20.7% idiopathic, 12.2% cholelithiasis, 3.7% miscellaneous causes |
83% unknown (common causes were excluded), 17% drug-induced |
Unknown |
Unknown |