Table 2. Univariate and Multivariate Analyses to Investigate Factors Predicting Response P Versus NP.
| Univariate |
Multivariate |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Age (years) | 1.060 | 0.998 - 1.127 | 0.059 | |||
| Sex (M vs. F) | 0.997 | 0.309 - 3.214 | 0.996 | |||
| Etiology (C vs. others) | 0.979 | 0.426 - 2.249 | 0.960 | |||
| Total bilirubin (mg/dL) | 4.166 | 1.396 - 12.432 | 0.011 | |||
| Prothrombin time (%) | 0.965 | 0.927 - 1.004 | 0.080 | |||
| Albumin (g/dL) | 0.629 | 0.248 - 1.596 | 0.329 | |||
| Platelets (× 104/µL) | 0.889 | 0.808 - 0.978 | 0.016 | |||
| AFP (≥ 10 vs. < 10) | 2.202 | 0.878 - 5.521 | 0.092 | |||
| PIVKA-II (≥ 75 vs. < 75) | 3.252 | 1.366 - 7.739 | 0.008 | 4.539 | 1.214 - 16.966 | 0.025 |
| Tumor number | 1.590 | 1.365 - 1.854 | 0.000 | 1.475 | 1.245 - 1.747 | 0.000 |
| Tumor size | 0.997 | 0.977 - 1.019 | 0.811 | |||
| Up to 7 (in vs. out) | 0.098 | 0.036 - 0.266 | 0.000 | |||
| Past TACE number | 1.711 | 1.333 - 2.194 | 0.000 | 1.472 | 1.058 - 2.048 | 0.022 |
HR: hazard ratio; M: male; F: female; C: hepatitis C virus; AFP: alfa-feto protein; PIVKA-II: protein induced by vitamin K absence-II.