Figure 1.

Mean (pg/mL) and percentage inhibition of IL-1α and IL-8 expression (A), and RQ and percentage inhibition of KLK5 and MMP-9 mRNA expression (B) after incubation of NHEK with dextran sulfate for 24 hours in a rosacea environment. IKK inhibitor was used as a positive control.

Note: Data shown are the mean of three independent experiments. **P<0.01 vs control cells.

Abbreviations: RQ, relative quantity; MMP-9, matrix metalloproteinase 9; NHEK, normal human epidermal keratinocyte; IKK, I kappa B kinase.