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. Author manuscript; available in PMC: 2018 Sep 12.
Published in final edited form as: J Alzheimers Dis. 2017;55(2):645–657. doi: 10.3233/JAD-160593

Table 3.

Associations of working memory performance with BDNF levels at baseline, with BDNF response and with BDNF post-intervention levels for the different interventions, stratified according to baseline BDNF levels

Intervention Physical exercise Cognitive training Mindfulness
BDNF outcomes Baseline level Response Post-interv level Baseline level Response Post-interv level Baseline level Response Post-interv level
All participants (N = 19) 0.25 p = 0.31 0.22 p = 0.38 0.50 p = 0.03 0.08 p = 0.74 0.09 p = 0.72 0.03 p = 0.90 −0.12 p = 0.63 −0.13 p = 0.60 −0.09 p = 0.72
Stratified by baseline BDNF Participants with lower levels (N = 6) −0.60 p = 0.21 0.89 p = 0.02 0.71 p = 0.11 0.07 p = 0.88 0.36 p = 0.43 0.32 p = 0.48 −0.03 p = 0.96 −0.20 p = 0.70 −0.37 p = 0.47
Participants with higher levels (N = 6) 0.71 p = 0.11 0.31 p = 0.54 0.77 p = 0.07 0.26 p = 0.63 −0.66 p = 0.16 −0.43 p = 0.40 0.26 p = 0.62 −0.37 p = 0.47 0.14 p = 0.79

All correlations were calculated between BDNF levels and the average maximum score on all CogMed items (see Methods).

Numbers are coefficients from Spearman correlations with exact p-values beneath.

The stratification of participants into lower versus higher baseline levels of BDNF was according to first and third tertiles.