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. 2018 Sep 4;12:617. doi: 10.3389/fnins.2018.00617

Table 4.

Methodological differences between the present study and Kanai et al. (2012).

Difference Here Kanai et al. (2012) Reason
Sample size and design n = 26, within-subject design n = 32, between-subject design More observations per cell, less influence of between-subject variability
FEF localization MRI-guided per individual Group MRI coordinate More power (Sack et al., 2009)
tDCS: duration 15 min 10 min More trials during stimulation; possibly increase tDCS effect
tDCS: location Right FEF Right or left FEF Right FEF is dominant (Duecker and Sack, 2015)
tDCS: montage FEF, contralateral forehead FEF, ipsilateral shoulder Decreased interelectrode distance increases effect (Moliadze et al., 2010; Opitz et al., 2015). Resembles canonical motor cortex montage
tDCS: conductive medium Ten20 conductive paste Saline soaked sponges Uniform electrode-skin contact, no risk of excess/leaking saline
Number of saccades per condition 180 (per 15 min) 40 (per 10 min) More robust estimates within each participant
Task: stimulus overlap No overlap of fixation and target Fixation point always on Possibility to analyze saccades back to fixation (center)
Task: placeholders None Target location marked with placeholders Spatial uncertainty might create more room for improvements in accuracy with tDCS
Task: ISI Exponential distribution: mean 500 ms, bounds 300–3,000 ms Normal distribution, bounds: 300–700 ms Temporally more unpredictable target onsets
Eye tracker: sampling rate 1,000 Hz 250 Hz More adequate resolution for small effects
Eye tracker: saccade threshold >30°/s velocity and >8000°/s2 acceleration >26.8°/s velocity Eyelink standards