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. 2018 Sep 6;13:5139–5158. doi: 10.2147/IJN.S167043

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© 2018 Liu et al. This work is published and licensed by Dove Medical Press Limited

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Cytotoxicity, in vitro cellular uptake, and anticancer effect of NPs.

Notes: (A) Cytotoxicity against MDA-MB231 cells, A549 cells, and HUVECs after incubation with FA-PEG-PLGA@ICG-Pfh NPs (Ptx-free) for 24 hours. (B) Cellular uptake of different groups; DAPI (blue) marks nuclei and DiI (red) PLGA NPs. (C) Anticancer efficacy of different therapies against MDA-MB231 cells. ^*P<0.05. Abbreviations: NPs, nanoparticles; HUVECs, human umbilical vein endothelial cells; FA, folic acid; PEG, polyethylene glycol; PLGA, poly(lactide-co-glycolic acid); Ptx, paclitaxel; ICG, indocyanine green; Pfh, perfluorohexane.

Cytotoxicity, in vitro cellular uptake, and anticancer effect of NPs.

Notes: (A) Cytotoxicity against MDA-MB231 cells, A549 cells, and HUVECs after incubation with FA-PEG-PLGA@ICG-Pfh NPs (Ptx-free) for 24 hours. (B) Cellular uptake of different groups; DAPI (blue) marks nuclei and DiI (red) PLGA NPs. (C) Anticancer efficacy of different therapies against MDA-MB231 cells. ^*P<0.05. Abbreviations: NPs, nanoparticles; HUVECs, human umbilical vein endothelial cells; FA, folic acid; PEG, polyethylene glycol; PLGA, poly(lactide-co-glycolic acid); Ptx, paclitaxel; ICG, indocyanine green; Pfh, perfluorohexane.