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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Adv Biosyst. 2017 Aug 18;1(10):1700083. doi: 10.1002/adbi.201700083

Figure 5. Two Distinct Populations in Embedded Spheroids.

Figure 5

Multiple researchers have observed the presence of two distinct subpopulations within an embedded spheroid. Shown here in a glioma embedded spheroid model, there is a dense core (identified by a circle on the left and an S on the right) and a migrating population (shown with a dashed circle on the left and an I on the right [78, 98]. Reprinted from reference 76 with permission from the JNS Publishing Group. Reprinted from reference 96 with permission from Elsevier