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Methods for the detection of RRM1 expression
| Method | RRM1 expression
|
No of studies (cases) | |
|---|---|---|---|
| High | Low | ||
| IHC | 539 (43.8%) | 692 (56.2%) | 15 (1,231) |
| PCR | 1,256 (55.5%) | 1,009 (44.5%) | 16 (2,265) |
| Total | 1,795 (51.3%) | 1,701 (48.7%) | 31 (3,496) |
Note: χ2 test indicated that there was significant difference between the two methods in the detection rate of RRM1 expression (χ2=43.46, P=0.000).
Abbreviations: IHC, immu nohistochemistry; RRM1, ribonucleotide reductase catalytic subunit M1.
