Table 3:
Prognostic factors associated with impaired overall survival in patients with localized extremity & trunk sarcoma (n = 23,579)
| Prognostic Factor | HR | 95% Cl | P-value | |
|---|---|---|---|---|
| Age (years) | 1.04 | 1.03 | 1.04 | <0.001 |
| Race (Ref White) | <0.001 | |||
| Black | 1.19 | 1.10 | 1.29 | |
| Hispanic | 1.03 | 0.92 | 1.15 | |
| Asian | 0.90 | 0.76 | 1.07 | |
| Other | 0.93 | 0.78 | 1.10 | |
| T stage (Ref T1) | <0.001 | |||
| T2 | 1.58 | 1.49 | 1.68 | |
| T3 | 2.12 | 1.97 | 2.28 | |
| T4 | 2.19 | 2.04 | 2.36 | |
| Unknown | 0.82 | 0.40 | 1.67 | |
| N1 disease | 3.31 | 2.76 | 3.97 | <0.001 |
| High grade | 2.34 | 2.21 | 2.47 | <0.001 |
| Margin (Ref RO) | ||||
| R1/R2 | 1.20 | 1.11 | 1.29 | <0.001 |
| Unknown | 1.25 | 1.16 | 1.34 | |
| Chemotherapy | 1.19 | 1.11 | 1.28 | <0.001 |
| Radiation therapy | 0.78 | 0.74 | 0.82 | <0.001 |
HR: hazard ratio; CI: confidence interval; Ref: reference value; N1: node positive; R0: negative microscopic margins, R1: positive microscopic margins; R2: positive gross margins