Table 2. KRASmt/SMAD4mt and Control cell lines.
Cell line | Group | Cancer type | KRAS | SMAD4 | SF2 |
---|---|---|---|---|---|
AsPC-1 | KRASmt/SMAD4mt | pancreatic | G12D | HD | 0.66 ± 0.13 |
PK-1 | KRASmt/SMAD4mt | pancreatic | G12D | HD | 0.50 |
SW1990 | KRASmt/SMAD4mt | pancreatic | G12D | HD | 0.56 ± 0.19 |
Capan-1 | KRASmt/SMAD4mt | pancreatic | G12V | S343* | 0.52 ± 0.24 |
CFPAC-1 | KRASmt/SMAD4mt | pancreatic | AMP, G12V | HD | 0.58 |
PSN1 | KRASmt/SMAD4mt | pancreatic | AMP, G12R | HD | 0.48 ± 0.00 |
T84 | KRASmt/SMAD4mt | colorectal | G12D | HD | 0.74 ± 0.28 |
SW403 | KRASmt/SMAD4mt | colorectal | G13V | HD | 0.59 |
SW480 | KRASmt/SMAD4mt | colorectal | AMP, G12V | HD | 0.67 ± 0.07 |
SW620 | KRASmt/SMAD4mt | colorectal | AMP, G12V | HD | 0.59 ± 0.16 |
AGS | KRASmt/SMAD4mt | stomach | G12D | HD | 0.45 ± 0.06 |
SW1573 | KRASmt/SMAD4mt | lung | G12C | HD | 0.60 ± 0.08 |
Capan-2 | Control | pancreatic | G12V | WT | 0.49 ± 0.04 |
MIAPaCa-2 | Control | pancreatic | G12C | WT | 0.49 ± 0.10 |
PANC-1 | Control | pancreatic | AMP | WT | 0.73 ± 0.20 |
HCT 116 | Control | colorectal | G13D | WT | 0.42 ± 0.10 |
LoVo | Control | colorectal | G13D | WT | 0.38 ± 0.10 |
LS180 | Control | colorectal | G12D | WT | 0.50 |
RKO | Control | colorectal | WT | WT | 0.33 ± 0.13 |
SW48 | Control | colorectal | WT | WT | 0.22 ± 0.06 |
NCI-N87 | Control | stomach | WT | HD | 0.39 ± 0.15 |
MKN-45 | Control | stomach | WT | HD | 0.65 ± 0.25 |
NCI-H1437 | Control | lung | WT | WT | 0.34 |
NCI-H1648 | Control | lung | WT | WT | 0.16 |
Abbreviations: AMP, amplification; HD, homozygous deletion; WT, wild type. SF2 data were obtained from previous publications, and the average ± standard deviation (if available) value for each cell line is shown (for details, see Acquisition of SF2 data from the literature in MATERIALS AND METHODS).