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. 2018 Aug 24;9(66):32642–32652. doi: 10.18632/oncotarget.25982

Table 2. KRASmt/SMAD4mt and Control cell lines.

Cell line Group Cancer type KRAS SMAD4 SF2
AsPC-1 KRASmt/SMAD4mt pancreatic G12D HD 0.66 ± 0.13
PK-1 KRASmt/SMAD4mt pancreatic G12D HD 0.50
SW1990 KRASmt/SMAD4mt pancreatic G12D HD 0.56 ± 0.19
Capan-1 KRASmt/SMAD4mt pancreatic G12V S343* 0.52 ± 0.24
CFPAC-1 KRASmt/SMAD4mt pancreatic AMP, G12V HD 0.58
PSN1 KRASmt/SMAD4mt pancreatic AMP, G12R HD 0.48 ± 0.00
T84 KRASmt/SMAD4mt colorectal G12D HD 0.74 ± 0.28
SW403 KRASmt/SMAD4mt colorectal G13V HD 0.59
SW480 KRASmt/SMAD4mt colorectal AMP, G12V HD 0.67 ± 0.07
SW620 KRASmt/SMAD4mt colorectal AMP, G12V HD 0.59 ± 0.16
AGS KRASmt/SMAD4mt stomach G12D HD 0.45 ± 0.06
SW1573 KRASmt/SMAD4mt lung G12C HD 0.60 ± 0.08
Capan-2 Control pancreatic G12V WT 0.49 ± 0.04
MIAPaCa-2 Control pancreatic G12C WT 0.49 ± 0.10
PANC-1 Control pancreatic AMP WT 0.73 ± 0.20
HCT 116 Control colorectal G13D WT 0.42 ± 0.10
LoVo Control colorectal G13D WT 0.38 ± 0.10
LS180 Control colorectal G12D WT 0.50
RKO Control colorectal WT WT 0.33 ± 0.13
SW48 Control colorectal WT WT 0.22 ± 0.06
NCI-N87 Control stomach WT HD 0.39 ± 0.15
MKN-45 Control stomach WT HD 0.65 ± 0.25
NCI-H1437 Control lung WT WT 0.34
NCI-H1648 Control lung WT WT 0.16

Abbreviations: AMP, amplification; HD, homozygous deletion; WT, wild type. SF2 data were obtained from previous publications, and the average ± standard deviation (if available) value for each cell line is shown (for details, see Acquisition of SF2 data from the literature in MATERIALS AND METHODS).