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. 2018 Aug 24;9(66):32653–32666. doi: 10.18632/oncotarget.25987

Figure 6. Comparison between FAP neoplasms and sporadic colorectal adenoma.

Figure 6

(A) Hierarchical clustering analysis of sporadic colorectal adenoma and normal mucosa samples. Infinium 450K data of 42 protruded adenoma and three sessile serrated adenoma (SSA) samples were obtained from GSE96540 and GSE48684. The 45 adenoma samples were stratified into four clusters, similar to sporadic CRC. H, HME; I, IME; L, LME; N, NME. Open box, protruded adenoma; closed box, SSA (bottom). (B) Comparison of methylation levels of methylation marker genes in FAP neoplasms and adenoma samples. Ad, sporadic colorectal adenoma; FAP, FAP neoplasms; N, normal mucosa.