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. 2018 Sep 12;9:3691. doi: 10.1038/s41467-018-06033-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Input–output communication transcriptional signature of SG neurons. a Differential expression of voltage-gated ion channels family among SG neurons. b, c Differential expression of neurotransmission systems including neurotransmitter (NT) receptors, peptides-related molecules, NT transporters, and synaptic vesicles (b) and of calcium-binding protein (c) among SG neurons (see also Supplementary Fig. 3). d Sketch of the SG neuron (SGN) synaptic connection with HC peripherally and with the cochlear nuclei (CN) in the brainstem. Arrows shows direction of the signal transmission. e, f Schematic representation of the transcriptional portrait of the post-synaptic (e) and pre-synaptic (f) sites of SG neuron types, based on differentially expressed gene shown in a, b