Table 3.
Baseline values and area under the curve (AUC) for change in the glucose, insulin and triglycerides in response to PL, FO, CC and CC-FO.
| Parameters | Time (min) | PL | FO | CC | CC-FO | Modela (time x treatment) P value | PLb VS FO | PLb VS CC | PLb VS CC-FO |
|---|---|---|---|---|---|---|---|---|---|
| Fasting glucose (mmol/L) |
0 | 5.3 ± 0.3 | 5.2 ± 0.37 | 5.4 ± 0.45 | 5.4 ± 0.48 | 0.441 | — | — | — |
| Glucose change AUC (mmol. min/L) |
0–120 | 2.7 ± 1.1 | 2.2 ± 1.2 | 1.73 ± 0.7 | 1.9 ± 1.0 | 0.007 | 0.105 | 0.003 | 0.004 |
| Fasting insulin (mIU/L) |
0 | 7.6 ± 2.5 | 8.2 ± 2.5 | 8.8 ± 3.7 | 9.0 ± 3.1 | 0.104 | — | — | — |
| Insulin change AUC (mIU. min/L) |
0–120 | 69.9 ± 53.1 | 57.4 ± 41.9 | 51.4 ± 45.1 | 51.9 ± 31.0 | 0.02 | 0.140 | 0.01 | 0.03 |
| Fasting triglycerides (mmol/L) |
0 | 1.0 ± 0.5 | 1.0 ± 0.3 | 1.1 ± 0.70 | 1.01 ± 0.38 | 0.534 | — | — | — |
| Triglycerides change AUC (mmol. min/L) |
0–120 | 0.3 (0.2, 0.5) |
0.4 (0.2, 0.6) |
0.2 (0.1, 0.6) |
0.52 (0.33, 0.72) |
0.100 | — | — | — |
Data are presented as mean ± SD or median (25th and 75th percentile). AUC – area under the curve. PL-double placebo, FO- fish oil alone, CC- curcumin alone, CC-FO- curcumin plus fish oil. aOutput from two-way repeated measures analysis of variance. bOutput from pair-wise analysis between the two groups.