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JZG could regulate the mTOR signalling. Hepatocytes were treated with PA (0.4 mM) in the presence or absence of either JZG (100 μg/mL) or rapamycin (2 μM) for 24 h. (A) Western blot analyses, the groupings were cropped from different gels subjected to identical conditions; (B) The progression of autophagic flux was visualized by a cell line stably expressing mCherry-p62. *P < 0.05, **P < 0.01, ***P < 0.001.
