Table 6.
Plasma and urine biochemical parameters.
| Sham LPD | Sham HPD | 1/2Nx LPD | 1/2Nx HPD | |
|---|---|---|---|---|
| Plasma phosphate (mmol/L) | 1.9 ± 0.2 | 2.1 ± 0.11 | 2.0 ± 0.13 | 2.1 ± 0.19 |
| Plasma ionized calcium (mM) | 1.3 ± 0.02 | 1.3 ± 0.01 | 1.3 ± 0.01 | 1.3 ± 0.02 |
| Plasma creatinine (μmol/L) | 44.2 ± 2.65 | 44.2 ± 0.88 | 61.8 ± 0.88a,b | 61.8 ± 1.76a,b |
| FEPi (%) | 0.4 ± 0.01 | 32.1 ± 7.49a | 0.7 ± 0.08b | 50.2 ± 7.03a,c |
| Plasma PTH (pg/ml) | 21.9 ± 0.20 | 72.1 ± 7.66a | 34.8 ± 4.26 | 65.9 ± 10.5a,c |
| Plasma FGF23 (pg/ml) | 130 ± 33.9 | 272 ± 24.0a | 119 ± 11.0b | 454 ± 49.8a,b,c |
ap < 0.05 vs Sham LPD; bp < 0.05 vs Sham HPD; cp < 0.05 vs 1/2Nx LPD.
LPD: Low Phosphate Diet; HPD: High Phosphate Diet.
FEPi: Fractional excretion of phosphate.
PTH: Parathyroid hormone.
FGF23: Fibroblast Growth Factor 23.