Skip to main content
. 2018 Sep 12;8:13673. doi: 10.1038/s41598-018-32079-w

Table 1.

Prediction results over the top 10 models.

Subset Method CASP11 CASP12 HOMSTRAD <Å (%) <2Å (%)
Commonai best 2.18 2.31 1.65 24 66
DaReUS-Loop 2.58 2.87 2.38 19 47
Rosetta NGK 2.96 3.34 2.71 12 35
GalaxyLoop-PS2 2.83 3.23 2.96 13 36
Commondb DaReUS-Loop 2.79 3.21 2.53 14 44
LoopIng 4.35 4.20 4.50 8 16
Sphinx 3.71 3.94 2.63 12 37
CommonHCai best 1.43 1.63 1.65 28 76
DaReUS-Loop 1.91 2.30 2.38 22 54
Rosetta NGK 2.59 2.99 2.71 14 38
GalaxyLoop-PS2 2.34 2.88 2.96 15 41
CommonHCdb DaReUS-Loop 2.05 2.25 2.53 17 53
LoopIng 3.66 3.53 4.50 10 20
Sphinx 2.90 3.19 2.63 14 42

Average flanked RMSD (Å) are reported for the CASP11, CASP12 and HOMSTRAD test sets, over the Common and CommonHC subsets. Comparison is between DaReUS-Loop, ab initio (ai) methods (Rosetta NGK and GalaxyLoop-PS2) and data-based (db) methods (LoopIng and Sphinx). All the RMSD values reported in this table correspond to the best flanked RMSD (Å) over 10 models. The “best” row shows the best candidate loop identified by DaReUS-Loop, before applying the filters or the top 10 selection. For Commonai and CommonHCai (resp. Commondb and CommonHCdb), the flanked RMSDs are calculated using flanks of 4 (reps. 2) amino acids. The percentage of highly accurate predictions (<1Å and <2Å) is also reported. Bold values correspond to the best values among all the methods.