Fundamental Characteristics of Aging Cells
(A) A schematic demonstrating the principle of cell alignment at birth (left) or to death (right). Individual cells' generational age is displayed within their representation.
(B) Mean division time as a function of age, with cells aligned to birth.
(C) Mean division time as a function of age, with cells aligned at death.
(D) Mean volume of cells as a function of age, with cells aligned to birth. The best-fit line from linear regression is shown.
(E) Mean volume of cells as a function of age, with cells aligned at death. N = 50 cells for all subfigures, with data points where less than 10 cells remained alive omitted. Error bars are SEM.