Figure 5.

Postmortem confocal microcopy images on mouse brains showing GFP-positive brain endothelium (green) and PKH-26-labeled RBC (red). (A, Top): PBS-RBC remain in the blood vessels (white arrows heads). (A, Bottom): t-BHP-treated RBC are inside (white arrow head) and outside the blood vessels (yellow arrow head), and also partially extravasated into the brain (blue arrow head). Orthogonal view showing PBS-treated RBC within the blood vessel (B, Top) and t-BHP-treated RBC partially and completely outside the blood vessel (B, Bottom). Scale bar = 50 μm.