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. 2018 Apr 6;2:41–50. doi: 10.1016/j.isci.2018.03.007

Figure 7.

Figure 7

Mutational Analysis of Ser81Thr

Mutation of Ser 81 to Thr splits the largest rigid cluster (LRC) (A: red) into two different pieces (B: green), indicating the key role of Ser 81 in maintaining the allosteric communication pathways within the LRC.