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. 2010 Jul 20;13(7):731–743. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2010.07.14

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杀伤细胞免疫球蛋白样受体(KIR)的家族成员

Killer cell Ig-like receptor (KIR) family members

基因名 别名 配基上的识别序列 配基的常见等位基因
*KIR2DL5 gene is duplicated and encoded by two separate loci within the LRC gene cluster; 127 AActivating KIR bind classical HLA molecules with low affinity; BThere are conflicting reports as to the HLA-C alleles that KIR2DS4 binds.76, 77
Note: Reprinted with permission from the copyright holder©2009 Landes Bioscience
KIR2DL5基因由LRC基因簇内两个单独的位点复制和编码[127]; A激活性KIR与经典HLA分子结合的亲和力较低;B与KIR2DS4结合的HLA-C等位基因的相关报道不一致。
注:本图得到版权所有者©2009 Landes Bioscience复制许可
KIR2DL1 CD158a, nkat1 HLA-C2 C2: Cw2, Cw4, Cw5, Cw6
KIR2DL2 CD158b1, nkat6 HLA-C1>HLA-C2 C1: Cw1, Cw3, Cw7, Cw8
KIR2DL3 CD158b2, nkat2 HLA-C1>HLA-C2 C1: Cw1, Cw3, Cw7, Cw8
KIR2DL5A* CD158f Unknown
KIR2DL5B* KIR2DL5.2 Unknown
KIR3DL1 NKB1, nkat3 HLA-Bw4 and some HLA-A B08, B27, B57, A24
KIR3DL2 CD158k, nkat4 Certain HLA-A allotypes A3, A11
KIR3DL3 CD158z Unknown
KIR2DL4 CD158d HLA-G
KIR2DS1 CD158h HLA-C2A C2: Cw2, Cw4, Cw5, Cw6
KIR2DS2 CD158j, nkat5 HLA-C1A C1: Cw1, Cw3, Cw7, Cw8
KIR2DS3 nkat7 HLA-C1A C1: Cw1, Cw3, Cw7, Cw8
KIR2DS4 CD158i, nkat8 disease peptide?; HLA-CA Cw3, Cw4B
KIR2DS5 CD158g, nkat9 Unknown
KIR3DS1 CD158e2, nkat10 HLA-Bw4?