Table 2. Univariable Linear Regression Analysis of 55 Individual Contact Lens Sensor Variables^a .

Variable	β (95% CI)	P Value
All bursts amplitude mean (per unit)	0.008 (−0.095 to 0.111)	.88
All bursts amplitude SD (per 0.1 U)	−0.003 (−0.017 to 0.010)	.60
All bursts OPA mean (per 0.01 U)	0.004 (−0.010 to 0.019)	.53
All bursts OPA SD (per 0.01 U)	0.030 (−0.006 to 0.067)	.11
All bursts OPF mean (per 10 U)	−0.006 (−0.062 to 0.048)	.81
All bursts OPF SD (per unit)	0.020 (−0.003 to 0.043)	.09
All bursts peak count mean (per unit)	0.002 (−0.010 to 0.015)	.69
All bursts peak count SD (per unit)	0.001 (−0.015 to 0.016)	.94
All bursts SD mean (per 0.1 U)	0.016 (−0.051 to 0.085)	.63
Amplitude (per 100 U)	−0.005 (−0.043 to 0.031)	.76
Amplitude of the cosine curve (per 100 U)	0.022 (−0.057 to 0.103)	.58
Auc sleep (per 10 U)	−0.000 (−0.015 to 0.013)	.92
Cosinor OPA acrophase (per 0.1 U)	0.004 (−0.012 to 0.022)	.59
Cosinor OPA amplitude (per 0.01 U)	0.010 (−0.013 to 0.033)	.39
Cosinor OPA mesor (per 0.01 U)	0.007 (−0.006 to 0.021)	.29
Day1 bursts amplitude mean (per unit)	−0.008 (−0.074 to 0.057)	.80
Day1 bursts amplitude SD (per unit)	0.027 (−0.108 to 0.161)	.70
Day1 bursts peak count mean (per unit)	−0.002 (−0.010 to 0.006)	.57
Day1 bursts peak count SD (per unit)	0.002 (−0.017 to 0.021)	.85
Day1 bursts SD mean (per 0.1 U)	−0.007 (−0.050 to 0.036)	.75
Level sleep start (per 100 U)	−0.090 (−0.182 to 0.001)	.05
Mean peak ratio 24 h (per 10 U)	−0.014 (−0.038 to 0.009)	.23
Mean peak ratio sleep (per 10 U)	0.000 (−0.020 to 0.021)	.97
Mean peak ratio wake (per 10 U)	−0.018 (−0.038 to 0.001)	.07
No. of brief peaks 24 h (per unit)	−0.016 (−0.049 to 0.017)	.34
No. of brief peaks sleep (per unit)	−0.029 (−0.087 to 0.030)	.34
No. of brief peaks wake (per unit)	−0.026 (−0.065 to 0.012)	.18
Night bursts amplitude mean (per 0.1 U)	0.017 (−0.003 to 0.038)	.11
Night bursts amplitude SD (per unit)	0.020 (−0.113 to 0.153)	.77
Night bursts OPA mean (per 0.01 U)	0.003 (−0.010 to 0.017)	.66
Night bursts OPA SD (per 0.1 U)	0.383 (−0.148 to 0.915)	.16
Night bursts OPF mean (per 10 U)	−0.014 (−0.068 to 0.040)	.62
Night bursts OPF SD (per unit)	0.020 (−0.007 to 0.047)	.15
Night bursts peak count mean (per unit)	0.024 (−0.033 to 0.082)	.40
Night bursts peak count SD (per unit)	−0.001 (−0.031 to 0.029)	.96
Night bursts SD mean (per 0.01 U)	0.014 (0.001 to 0.027)	.04
No. of long peaks 24 h (per unit)	0.008 (−0.005 to 0.021)	.24
No. of long peaks sleep (per unit)	0.023 (−0.011 to 0.057)	.18
No. of brief peaks wake (per unit)	0.007 (−0.010 to 0.024)	.43
OPA maximum (per 0.01 U)	0.003 (−0.005 to 0.012)	.42
OPA minimum (per 0.01 U)	−0.003 (−0.002 to 0.001)	.75
OPA night amplitude smoothed (per 0.1 U)	0.054 (−0.134 to 0.243)	.57
OPA night delta (per 0.1 U)	−0.042 (−0.139 to 0.055)	.39
OPA night delta smoothed (per 0.1 U)	−0.045 (−0.187 to 0.096)	.53
OPA night noise (per 0.01 U)	0.055 (−0.012 to 0.012)	.11
OPA SD (per 0.01 U)	0.037 (−0.016 to 0.090)	.17
SD (per 100 U)	0.023 (−0.094 to 0.140)	.70
Tojo (per 100 U)b	0.019 (−0.027 to 0.066)	.42
Variability from mean 24 h (per 100 U)	0.064 (−0.062 to 0.191)	.32
Variability from mean sleep (per 100 U)	0.016 (−0.180 to 0.214)	.87
Variability from mean wake (per 100 U)	−0.015 (−0.136 to 0.105)	.80
Variability from smooth 24 h (per 10 U)	−0.076 (−0.202 to 0.049)	.23
Variability from smooth sleep (per 10 U)	0.139 (0.007 to 0.271)	.04
Variability from smooth wake (per 10 U)	−0.113 (−0.210 to −0.015)	.02
Wake-to-sleep slope (per 100 U)	0.141 (0.041 to 0.240)	.005

Abbreviations: AUC, area under the curve; OPA, ocular pulse amplitude; OPF, ocular pulse frequency.

^aThe dependent variable is the mean deviation slope in decibels per year.

^bThis feature is defined as maximum (Triggerfish burst curve during sleep) − minimum (Triggerfish burst curve during sleep). By Triggerfish burst curve we mean the curve composed of the 288 medians from the actual curve.¹⁹