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. 2013 Sep 27;2(5):437–445. doi: 10.2217/cns.13.31

Table 2. . Spine Instability Neoplastic Score.

SINS component Score
Location

Junctional (occiput–C2, C7–T2, T11–L1, L5–S1) 3

Mobile spine (C3–C6, L2–L4) 2

Semirigid (T3–T10) 1

Rigid (S2–S5) 0

Pain

Yes 3

Occasional pain but not mechanical 1

Pain-free lesion 0

Bone lesion

Lytic 2

Mixed (lytic/blastic) 1

Blastic 0

Radiographic spinal alignment

Sublaxation/translation present 4

De novo deformity (kyphosis/scoliosis) 2

Normal alignment 0

Vertebral body collapse

>50% collapse 3

<50% collapse 2

No collapse with >50% of body involved 1

None of the above 0

Posterolateral involvement of spinal elements

Bilateral 3

Unilateral 1

None of the above 0

Pain improvement with recumbency and/or pain with movement/loading of spine.

Facet, pedicle or costovertebral joint fracture or replacement with tumor.

SINS: Spinal Instability Neoplastic Score.

Adapted with permission from [52].