Table 1.
Clinical characteristics of the studied patients.
| Minor edema (n = 80) | Significant edema (n = 28) | p value | |
|---|---|---|---|
| Age, mean (SD) | 75.0 (11.5) | 71.9 (11.7) | 0.469 |
| Male gender, n (%) | 38 (47.5) | 15 (53.6) | 0.582 |
| Vascular risk factors | |||
| Arterial hypertension | 66 (85.7) | 23 (85.2) | 0.946 |
| Diabetes mellitus | 17 (22.1) | 6 (22.2) | 0.988 |
| Dyslipidemia | 54 (70.1) | 13 (48.1) | 0.061 |
| Smoking | 5 (5.3) | 1 (3.6) | 0.664 |
| Atrial fibrillation | 42 (54.5) | 13 (46.4) | 0.461 |
| Coronary disease | 8 (11.8) | 2 (7.4) | 0.533 |
| Obesity | 14 (20.6) | 6 (22.2) | 0.631 |
| Peripheral artery disease | 3 (4.5) | 2 (7.4) | 0.567 |
| Baseline NIHSS, mean (SD) | 16.9 (7.2) | 17.7 (5.6) | 0.138 |
| ASPECTS at admission, median (IQR) | 9 (1.75) | 7 (3) | <0.001 |
| Thrombus location, n (%) | 0.354 | ||
| Distal ICA | 2 (2.5) | 2 (7.1) | |
| M1–MCA | 68 (85.0) | 19 (67.9) | |
| ICA + M1–MCA | 10 (12.5) | 7 (25.0) | |
| IV fibrinolysis | 80 (100.0) | 28 (100.0) | |
| Mechanical thrombectomy | 21 (26.3) | 8 (28.6) | 0.297 |
| Recanalization at six hours | 59 (73.8) | 10 (35.7) | <0.001 |
| Hemorrhagic transformation (PH2) | 1 (1.3) | 5 (17.9) | 0.002 |
| Good CPC score, n (%) | 58 (72.5) | 11 (39.3) | <0.001 |
The p values shown are the results of comparison of both groups (minor and significant edema) for the corresponding variable.
ASPECTS: Alberta Stroke Program Early Computed Tomography Score; CPC: collateral pial circulation; ICA: internal carotid artery; IQR: interquartile range; IV: intravenous; MCA: middle cerebral artery; NIHSS: National Institutes of Health Stroke Scale; PH: parenchymal hematoma; p-values in bold are significant.