Table 4.
Treatments and outcomes of the studies.
| Author | Agglutination titer | Operation | Pathogen | Antibiotic treatment | Duration (months) | Follow up (years) | Outcome |
|---|---|---|---|---|---|---|---|
| Carothers | NA | Yes (2 stage) | B. abortus | Rifampin 600 mg, doxycycline 200 mg | 5 | 2 | No reinfection |
| Erdogan | 640 | No | B. melitensis | Rifampin 600 mg, doxycycline 200 mg | 4 | 3 | No reinfection |
| Dauty | NA | Yes (2 stage) | B. melitensis | Rifampin 900 mg, vibramycin 200 mg | 1.5 | 10 | No reinfection |
| Tassinari | 800 | No | B. melitensis | Rifampin 250 mg, doxycycline 200 mg | 2 | 1 | No reinfection |
| Tena | 80 | Yes (2 stage) | B. melitensis | Rifampin 900 mg, doxycycline 200 mg | 2 | 4 | No reinfection |
| Ruiz-Iban | NA | Yes (2 stage) | B. abortus | Rifampin 900 mg, doxycycline 200 mg | 1.5 | 5.5 | No reinfection |
| 640 | Yes (drainage) | B. melitensis | Rifampin 900 mg, SM 1 g, doxycycline 200 mg | 6 | 5 | No reinfection | |
| Cairo | 320 | No | B. melitensis | Doxycycline 200 mg, SM 1 g | 26 | 5 | No reinfection |
| NA | Yes (1 stage) | B. melitensis | Rifampin 600 mg doxycycline 200 mg, SM 750 mg | 6 | 3 | No reinfection, radiolucent line at the femoral interface | |
| Kasim | 80 | Yes (1 stage) | B. abortus | Vibramycin 200 mg, rifampin 600 mg | 5 | 4 | No reinfection, |
| Weil | 1600 | Yes (2 stage) | B. melitensis | Rifampin 600 mg doxycycline 200 mg | 1.5 | 1 | No reinfection |
| 1600 | Yes (2 stage) | B. melitensis | Rifampin 600 mg doxycycline 200 mg | 1.5 | 1 | No reinfection | |
| 1600 | Yes (2 stage) | B. melitensis | Rifampin 600 mg doxycycline 200 mg | 1.5 | 1 | No reinfection | |
| Ortega-Andreu | NA | Yes (2 stage) | B. melitensis | Rifampin 900 mg, SM 1 g, doxycycline 200 mg | 3 | 0.5 | No reinfection |
| Orti | 160 | No | B. melitensis | Rifampin 900 mg, SM 1 g, doxycycline 200 mg | 1.5 | 0.7 | No reinfection |
| Malizos | 160 | No | B. melitensis | SM 1 g, doxycycline 200 mg, Septrin Forte twice | 7 | 2.6 | No reinfection |
| Agarwal | 2560 | No | B. melitensis | Rifampin 300 mg, two septra tablets | 19 | 1.6 | No reinfection |
| Jones | 640 | Yes (1 stage) | B. abortus | Tetracycline 2 g, SM 1 g | 12 | 3 | No reinfection |
NA, not available; SM, streptomycin.