Table 1. Blood chemistry and clinical data of the affected and normal individuals of the studied family.
| Characteristics | Patients (n = 10) | Control (n = 24) | P-value |
|---|---|---|---|
| Age (Years) | 22.5 ± 16.8 | 26.5 ± 14.6 | NS |
| Male: Female | 5:5 | 12:12 | 1 |
| BMI (kg/m2) | 20 ± 3.2 | 21 ± 3.6 | NS |
| TC (mg/dL) | 422.2 ± 181.5 | 184.9 ± 32.5 | < 0.0001 |
| TG (mg/dL) | 167.6 ± 67.1 | 135.7 ± 80.1 | 0.28 |
| LDL-C (mg/dL) | 323.6 ± 149.6 | 108.5 ± 26.8 | < 0.0001 |
| HDL-C (mg/dL) | 38 ± 8.4 | 45.0 ± 11.0 | 0.084 |
| Paraoxonase activity (U/L) | 116.5 ± 40.3 | 172.5 ± 61.6 | 0.001 |
| Arylesterase activity (kU/L) | 168.3 ± 24.8 | 210.7 ± 37.9 | 0.002 |
| Xanthomas | 1 (10%) | 0 (0%) | — |
| CHD | 1 (10%) | 0 (0%) | — |
Values are given as means ± SD (p < 0.05), continuous variables were analyzed using ANOVA whereas categorical variables were compared by Chi-square. NS: not statistically significant; BMI: body mass index; TC: serum total cholesterol; TG: serum total triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; CHD: coronary heart disease risk.