Table 2. Paraoxonase-1 allele, genotype, and haplotype distributions of L55M and Q192R polymorphisms in patients and healthy individuals of the hypercholesterolemia family.

	Characteristics (Allele/Genotypes)	Patients (n = 10)	Controls (n = 24)	p
Alleles	L55	2 (10%)	2 (4.2%)	0.336
	M55	18 (90%)	46 (95.8%)	0.927
	Q192	19 (95%)	33 (68.7%)	0.0164
	R192	1 (5%)	15 (62%)	0.998
Genotypes	L55L55	0 (0%)	0 (0%)	1
	L55M55	2 (20%)	2 (8.3%)	0.334
	M55M55	8 (80%)	22 (91.7%)	0.933
	Q192Q192	9 (90%)	10 (41.7%)	0.0113
	Q192R192	1 (10%)	13 (54.2%)	0.999
	R192R192	0 (0%)	1 (4.2%)	1
Haplotypes	M55M55/Q192Q192	8 (80%)	8 (33.3%)	0.017
	L55M55/Q192Q192	1 (10%)	2 (8.3%)	0.661
	L55M55/Q192R192	1 (10%)	0 (0%)	0.294
	M55M55/Q192R192	0 (0%)	13 (54.2%)	1
	M55M55/R192R192	0 (0%)	1 (4.2%)	1

p < 0.05 was considered statistically significant; data were analyzed using Fisher’s Exact Test.