Figure 4. Interaction analysis between ABA-dependent and ABA-independent drought-responsive genes. (A) Statistical significance of the global interactions between ABA-dependent and ABA-independent drought-responsive genes. The significance of interactions among drought-responsive gene sets was calculated using t-tests by comparing the Z-scores of the interactions of DEGs and non-DEGs. The random gene sets were selected from the pool of Non-DEGs of the same size as the drought-responsive gene sets to calculate the Z-score. The boxplots indicate inter-quartile ranges of the data. The bar in each boxplot indicates the median. (B) Network view of interaction between ABA-dependent and ABA-independent drought-responsive genes. ABA-dependent DEGs are depicted in orange, and ABA-independent DEGs are depicted in blue. The interactions connecting the nodes are represented by color-coded lines according to the experimental verification status. Gray represents the predicted interaction without experimental verification; red represents the predicted interaction with experimental verification. The line width represents the probability of the protein pairs interacting.