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Ultrafine PM treatment decreased the vascular relaxation response in isolated young SOD2+/− and WT mouse aortic rings. Nitroglycerine (NTG) induced relaxation (% of peak PE response) of aortic rings pre-constricted with 1μmol/L phenylephrine (PE). N=6–8 mice each group. *p<0.05 ultrafine PM treated young WT (UF-WT-Y) vs. untreated young WT aortic rings (WT-Y), and #p<0.05 ultrafine PM treated young SOD (UF-SOD-Y) vs. untreated young SOD (SOD-Y) aortic rings.
