Table 2.
Intraoperative variables by group, PVB vs no PVB.
| Intraoperative Effects of PVB | |||||||
|---|---|---|---|---|---|---|---|
| PVB (n=66) | No PVB (n=104) | p | |||||
| Intraoperative Variables | |||||||
| Mean | SE | Mean | SE | p | |||
| Intraop Heart Rate | 81.0 | ± | 8.8 | 80.7 | ± | 9.0 | 0.8 |
| Intraop MAPa (mmHg) | 69.0 | ± | 7.0 | 68.3 | ± | 6.6 | 0.5 |
| Intraop SBP (mmHg) | 105.6 | ± | 9.5 | 106.1 | ± | 8.1 | 0.7 |
| Intraop DBP (mmHg) | 57.7 | ± | 7.0 | 56.9 | ± | 7.6 | 0.5 |
| Time MAP < 65mmHg (min) | 216.7 | ± | 167.9 | 255.4 | ± | 180.2 | 0.5 |
| AUC MAP <65mmHg | 1433.1 | ± | 1687.8 | 1806.9 | ± | 1692.9 | 0.16 |
| Time MAP <80% baseline (min) | 336.1 | ± | 214.8 | 340.5 | ± | 228.1 | 0.9 |
| AUC <80% of baseline | 3747.4 | ± | 4124.3 | 3999.2 | ± | 4124.3 | 0.70 |
| MAC | 0.93 | ± | 0.1 | 0.95 | ± | 0.1 | 0.4 |
| Intraop Crystalloid (mL) | 4073.3 | ± | 1365.5 | 3841.8 | ± | 1217.4 | 0.3 |
| Total Crystalloid (mL) | 4476.7 | ± | 1350.5 | 4128.3 | ± | 1214.8 | 0.1 |
| Total Colloid (mL) | 463.1 | ± | 150.0 | 716.3 | ± | 264.7 | <0.01 |
| PRBC, n (%) | 1.0 | 0.0 | 3.0 | 0.0 | 1.0 | ||
| Vasopressors, n (%) | 30.0 | 0.4 | 39.0 | 0.6 | 0.3 | ||
| Vasopressor doses | 4.1 | ± | 3.8 | 3.9 | ± | 4.2 | 0.8 |
| Medication Requirement | |||||||
| Baseline Narcotic Use (mg/day) | 2.5 | ± | 1.2 | 1.7 | ± | 6.0 | 0.52 |
| Pre-op Narcoticb (mg) | 26.2 | ± | 1.2 | 3.0 | ± | 1.0 | <0.01 |
| Intra-op Narcotic (mg) | 96.3 | ± | 10.3 | 161.2 | ± | 8.2 | <0.01 |
| Post-op Narcotic (mg) | 10.1 | ± | 1.9 | 7.4 | ± | 1.5 | 0.27 |
| Total Narcotic (mg) | 132.6 | ± | 78.5 | 171.6 | ± | 92.2 | <0.01 |
| Baseline Benzodiazepine (mg/day) | 27.1 | ± | 124.4 | 10.0 | ± | 49.5 | 0.29 |
| Pre-op Benzodiazepineb (mg) | 3.5 | ± | 0.2 | 2.3 | ± | 0.2 | <0.01 |
| Intra-op Benzodiazepine (mg) | 2.3 | ± | 0.2 | 1.7 | ± | 0.2 | 0.09 |
| Post-op Benzodiazepine (mg) | 0.03 | ± | 0.03 | 0.04 | ± | 0.02 | 0.72 |
| Total Benzodiazepine use (mg) | 5.8 | ± | 2.9 | 4.0 | ± | 2.3 | <0.01 |
a
Intraoperative MAP, SBP, and DBP, and minutes with MAP < 65mmhg were adjusted for preoperative values.
b
Preoperative, intraoperative, post-operative, and total narcotic and benzodiazepine requirements were adjusted for baseline use. Narcotic use is reported in IV morphine equivalents. Benzodiazepine use is reported in IV midazolam equivalents.