Table 4.
Intraoperative variables by ERAS protocol vs PVB block alone.
| Intraoperative Effects of ERAS | |||||||
|---|---|---|---|---|---|---|---|
| ERAS (n=19) | No ERAS (n=47) | P | |||||
| Intraoperative Variables | |||||||
| Mean | SD | Mean | SD | P | |||
| Intraop Heart Rate | 81.2 | ± | 7.3 | 81.5 | ± | 9.4 | 0.87 |
| Intraop MAP (mmHg) | 67.4 | ± | 3.3 | 69.7 | ± | 7.9 | 0.23 |
| Intraop SBP (mmHg) | 105.7 | ± | 5.4 | 105.4 | ± | 10.6 | 0.89 |
| Intraop DBP (mmHg) | 56.4 | ± | 3.8 | 58.2 | ± | 7.8 | 0.28 |
| Time MAP < 65mmHg (min) | 245.3 | ± | 108.5 | 202.7 | ± | 186.2 | 0.25 |
| AUC MAP <65mmHg | 1440.9 | ± | 906.0 | 1430.0 | ± | 1924.6 | <0.01 |
| Time MAP <80% baseline (min) | 264.8 | ± | 155.4 | 364.9 | ± | 229.8 | 0.09 |
| AUC <80% baseline | 1997.5 | ± | 1959.4 | 4454.8 | ± | 4794.9 | 0.93 |
| MAC | 0.88 | ± | 0.1 | 0.94 | ± | 0.1 | 0.05 |
| Intraop Crystalloid (mL) | 4016.9 | ± | 1028.2 | 4096.2 | ± | 1489.8 | 0.83 |
| Total Crystalloid (mL) | 4391.3 | ± | 917.5 | 4511.2 | ± | 1497.9 | 0.69 |
| Total Colloid (mL) | 447.4 | ± | 157.7 | 470.2 | ± | 148.2 | 0.59 |
| PRBC, n (%) | 1.0 | 0.1 | 0.0 | 0.0 | 0.29 | ||
| Pressors, n (%) | 9.0 | 0.5 | 21.0 | 0.4 | 1.00 | ||
| Pressor doses | 4.4 | ± | 5.2 | 4 | ± | 3.2 | 0.77 |
| Medication Requirement | |||||||
| Baseline Narcotic Use (mg/day) | 1.2 | ± | 0.5 | 3.0 | ± | 1.1 | 0.35 |
| Pre-op Narcotic (mg) | 35.1 | ± | 2.6 | 22.6 | ± | 1.7 | <0.01 |
| Intra-op Narcotic (mg) | 49.5 | ± | 13.9 | 114.4 | ± | 8.8 | <0.01 |
| Post-op Narcotic (mg) | 10.27 | ± | 4.1 | 9.9 | ± | 2.6 | 0.94 |
| Total Narcotic (mg) | 95.2 | ± | 146.9 | ± | 9.3 | 0.01 | |
| Baseline Benzodiazepine (mg/day) | 13.2 | ± | 57.6 | 32.7 | ± | 143.1 | 0.43 |
| Pre-op Benzodiazepine (mg) | 3.4 | ± | 0.4 | 3.5 | ± | 0.2 | 0.74 |
| Intra-op Benzodiazepine (mg) | 4.2 | ± | 0.5 | 1.5 | ± | 0.3 | <0.01 |
| Post-op Benzodiazepine (mg) | 0.1 | ± | 0.04 | 0.02 | ± | 0.03 | 0.48 |
| Total Benzodiazepine use (mg) | 7.6 | ± | 0.4 | 5.1 | ± | 0.2 | 0.01 |
a
Intraoperative MAP, SBP, and DBP, and minutes with MAP < 65mmhg were adjusted for preoperative values.
b
Preoperative, intraoperative, post-operative, and total narcotic and benzodiazepine requirements were adjusted for baseline use. Narcotic use is reported in IV morphine equivalents. Benzodiazepine use is reported in IV midazolam equivilents.