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. Author manuscript; available in PMC: 2019 Sep 11.
Published in final edited form as: J Am Coll Cardiol. 2018 Sep 11;72(11):1252–1263. doi: 10.1016/j.jacc.2018.05.077

Table 5:

Net reclassification of 10-year cardiovascular disease risk into low (<5%), intermediate (5% - <10%), and high (≥10%) risk groups, comparing model A (based on established CVD risk factors) to model B (based on established CVD risk factors plus hypertensive disorders of pregnancy and parity) among women with incident CVD and those without incident CVD

Model B: Established Risk Factors Plus Hypertensive Disorders of Pregnancy and Parity
Categories of Predicted 10-Year Risk
Model A: Established Risk Factors Low Risk: Intermediate Risk: High Risk: Total
Categories of Predicted 10-Year Risk <5% 5%–<10% >10% Reclassified

Women with incident CVD (n=685)

Low Risk: <5%
    N 669 4 0 4
    % Reclassified --- 0.6 --- 0.6
Intermediate Risk: 5% - <10%
    N 1 11 0 1
    % Reclassified 8.3 --- --- 8.3
High Risk: >10%
    N 0 0 0 ---
    % Reclassified --- --- --- ---

Women without incident CVD (n=105,545)

Low Risk: <5%
    N 105,293 60 0 60
    % Reclassified --- 0.06 --- 0.06
Intermediate Risk: 5% - <10%
    N 27 153 4 31
    % Reclassified 14.7 --- 2.2 16.9
High Risk: >10%
    N 0 2 6 2
    % Reclassified --- 25.0 --- 25.0

Abbreviations: CVD: cardiovascular disease. Established risk factors include age, total cholesterol, high-density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetes.

NRI = 0.004; 95% CI: -0.002, 0.010; P = 0.26. NRI for events = 0.004; 95% CI: -0.002, 0.010; P = 0.21. NRI for non-events = -0.0003; 95% CI: -0.0005, -0.0002; P = 0.0003.