Online Table 4:

Net reclassification of 10-year cardiovascular disease risk into low (<5%), intermediate (5% - <10%), and high (≥10%) risk groups, comparing model A (based on established CVD risk factors) to model B (based on established CVD risk factors plus hypertensive disorders of pregnancy and parity) among women with incident CVD and those without incident CVD at ages 50–59

	Model B: Established CVD Risk Factors
	Plus Hypertensive Disorders of Pregnancy and Parity
	Categories of Predicted 10-Year Risk
Model A : Established CVD Risk Factors	Low Risk:	Intermediate Risk:	High Risk:	Total
Categories of Predicted 10-Year Risk	<5%	5%–<10%	≥10%	Reclassified
Women with incident CVD (n=326)
Low Risk: <5%
N	314	2	0	2
% Reclassified	---	0.6	---	0.6
Intermediate Risk: 5% - <10%
N	0	10	0
% Reclassified	---	---	---	---
High Risk: ≥10%
N	0	0	0
% Reclassified	---	---	---	---
Women without incident CVD (n=31,852)
Low Risk: <5%
N	31,666	15	0	15
% Reclassified	---	0.05	---	0.05
Intermediate Risk: 5% - <10%
N	14	150	0	14
% Reclassified	8.5	---	---	8.5
High Risk: ≥10%
N	0	1	6	1
% Reclassified	---	14.3	---	14.3

Abbreviation: CVD: cardiovascular disease. Established risk factors include age, total cholesterol, high-density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetes. NRI = 0.006; 95% CI: -0.0002, 0.014; P = 0.13. NRI for events = 0.006; 95% CI: 0.000, 0.014; P = 0.13. NRI for non-events = 0.000; 95% CI: -0.0003, 0.0003; P = 0.99.